Pain is a burden for people with hemophilia (PwH) and is often underdiagnosed. Therefore, it is crucial to develop accurate tools for pain assessment. Pain pressure thresholds (PPTs) are valuable in the...
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Hemophilia A and B are X-linked bleeding disorders caused by mutations in the F8 and F9 genes, leading to deficiencies in coagulation factors VIII (FVIII) and IX (FIX), respectively....
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Little is known on the mechanisms of tolerance to factor VIII (FVIII) in haemophilia A (HA) patients. To identify immunological markers in tolerance development, samples from two patients with HA treated...
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We compared patient-reported outcomes (PROs) in persons with hemophilia A (PwHA) by inhibitor status and prescribed treatment products. Methods: Hematology Utilization Group VIII study enrolled PwHA aged ≥ 2 years to collect PRO data via surveys. A clinical chart review documented the hemophilic severity, inhibitor level and treatment regimen. PROs were compared across inhibitor status and prescribed treatment products. Results: Among 85 enrolled...
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